Reason has followed up on an Sky News story with an
article by Ronald Bailey July 1 reporting studies in Sweden and Germany that
show that many people have T-cell response that will protect them from
coronavirus exposures (except maybe very large ones).
Sweden approaches with caution: it is not clear yet whether you have protection
from cellular immunity alone after antibodies die off. It is common with other
infectious agents that you do, or that cellular immunity makes your symptoms
from a subsequent case trivial.
This may be interesting to protesters and journalists
who march with them to film them. Unlike
people going to bars, birthday house parties and church services, protesters
seem to be staying on good health for the most part. Most have worn masks. But the scream and holler a lot. I have heard of cases where people say they
have tested negative by PCR despite marching in these events. Antibody tests aren’t as common but it is
likely many have antibodies for a while.
I notice this with my own body aging. I stopped having strep throats after having
them 2 or 3 times in my 40s. I’ve had
norovirus once (in 2009) in the past 20 years, whereas as a youngster it was
common. A serious deep dental bone infection
in 2004 never returned. All of these
suggest cellular immunity, not antibodies.
But cellular immunity can also drive cytokine storms. The important thing with the coronavirus is that
the response needs to be proportional to need right after infection. Genes and blood type may matter.
We should be studying the T-cell response of people with
asymptomatic or “mild” COVID, and with people who test negative on PCR but who
have at least one positive antibody test.
This may suggest ways of designing better drugs as prophylactics or help
with vaccines.
An earlier video from Medcram explains a particular hooker: Sars-Cov2 can actually invade a T4 cell but cannot reproduce inside it (unlike HIV). Also another possible complication if antibody dependent enhancement (ADE) from IgM antibodies. PeakProsperity has mentioned this, and I'll look further.
Update: July 10
Swedish study (in pre-print) examines T-cell immunity, which is more like a "resistance" rather than absence of infection. That's why the 4 minor coronaviruses are harmless to humans with normal cellular immunity. Humans have had time to learn to deal with them.
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